%0 Journal Article %T Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment %A Hiroshi Tsumura %A Ichiro Itonaga %A Kazuhiro Tanaka %A Masanori Kawano %A Tatsuya Iwasaki %J Archive of "Cell Communication and Signaling : CCS". %D 2018 %R 10.1186/s12964-018-0225-2 %X The expression of IL-8 in mono-cultured and co-cultured osteosarcoma and normal cells. a Relative expression of IL-8 mRNA in hMSC and MG63. b Relative expression of IL-8 mRNA in MRC 5 and MG63. c Changes in gene expression in hMSCs after the co-culture with MG63. d Changes in gene expression in MG63 after the co-culture with hMSC %K Interleukin-8 %K Osteosarcoma %K Mesenchymal stem cells %K Tumor proliferation and metastasis %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889532/