BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

a Dot plot bioinformatics analysis showing BRD9 expression in publicly available RNA-seq data from 200 primary AML samples, 19 samples of human hematopoietic progenitors, and 16 samples of differentiated human monocyte and macrophage cells. β-Actin was used as housekeeping gene (P？<？0.01 Welch’s t-test). b RT-qPCR analysis of BRD9 expression in primary AML samples (pt) compared with CD34+ cells; error bars indicate SD of three biological replicates (*P？<？0.05, **P？≤？0.01). c WB analysis of BRD9 in the indicated leukemic cell lines compared with the CD34+. Actin was used as loading control. Error bars indicate SD of three biological replicates (*P？<？0.05, **P？≤？0.01