LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer

BCAR4 expression was significantly increased in CRC cells and ALDH+ cells. a, b qRT-PCR results revealed that expression of BCAR4 in CRC tissues and several CRC cell lines (HCT-116, SW480, HCT-8). c, d qRT-PCR was used to examine the expression of ALDH, CD133, SOX2, NANOG, OCT4, CD44, Lgr5 and BCAR4 in ALDH+ or ALDH？ CRC cells. *P？<？0.05, **P？<？0.01, ***P？<？0.001 vs. contro