%0 Journal Article
%T LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer
%A Maijian Wang
%A Ming Xie
%A Shurui Ouyang
%A Xin Zhou
%A Xinbin Zheng
%A Zhengquan Chen
%J Archive of "Cancer Cell International".
%D 2019
%R 10.1186/s12935-019-0784-3
%X BCAR4 expression was significantly increased in CRC cells and ALDH+ cells. a, b qRT-PCR results revealed that expression of BCAR4 in CRC tissues and several CRC cell lines (HCT-116, SW480, HCT-8). c, d qRT-PCR was used to examine the expression of ALDH, CD133, SOX2, NANOG, OCT4, CD44, Lgr5 and BCAR4 in ALDH+ or ALDH£¿ CRC cells. *P£¿<£¿0.05, **P£¿<£¿0.01, ***P£¿<£¿0.001 vs. contro
%K Breast cancer anti-estrogen resistance 4 (BCAR4)
%K Colorectal cancer (CRC)
%K LncRNA
%K ALDH+ cancer stem/initiating cells
%K miR-665
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438025/