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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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Discovery of a Selective Phosphoinositide-3-Kinase
(PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical
Candidate
DOI: 10.1021/acsmedchemlett.6b00238
André Lescarbeau, Ann M. Rowley, Catherine A. Evans, Christian M. Martin, Culver Cheung, David G. Winkler, Erin E. Brophy, Erin L. O’Hearn, Janid A. Ali, Jennifer
L. Proctor, Jennifer G. Hoyt, Johan A. Pradeilles, John R. Soglia, Jonathan
P. DiNitto, Louis Grenier, Martin R. Tremblay, Melissa M. Pink, Patrick O’Hearn, Quentin Glenadel, Somarajan J. Nair, Stanley I. Goldstein, Tao Liu, Thomas Tibbitts, Vito J. Palombella
Keywords: IPI-549, PI3K-gamma inhibitor, phosphoinositide-3-kinase, isoform selectivity, neutrophil migration, immuno-oncology
Abstract:
Full-Text
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