Design and Synthesis of mGlu2 NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core

DOI: 10.1021/acsmedchemlett.7b00279

Keywords: Negative allosteric modulator (NAM), metabotropic glutamate receptor 2 (mGlu2), depression, VU6001966, CNS penetration

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