%0 Journal Article
%T Design and Synthesis of mGlu2 NAMs with
Improved Potency and CNS Penetration Based on a Truncated Picolinamide
Core
%A Alice L. Rodriguez
%A Andrew S. Felts
%A Anna L. Blobaum
%A Carrie K. Jones
%A Christopher J. Brassard
%A Colleen M. Niswender
%A Craig W. Lindsley
%A Hyekyung P. Cho
%A Julie L. Engers
%A Katrina
A. Bollinger
%A Kyle A. Emmitte
%A Michael Bubser
%A P. Jeffrey Conn
%A Rebecca L. Weiner
%A Sichen Chang
%J Archive of "ACS Medicinal Chemistry Letters".
%D 2017
%R 10.1021/acsmedchemlett.7b00279
%K Negative allosteric modulator (NAM)
%K metabotropic glutamate receptor 2 (mGlu2)
%K depression
%K VU6001966
%K CNS penetration
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601377/