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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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Discovery of Clinical Development Candidate GDC-0084,
a Brain Penetrant Inhibitor of PI3K and mTOR
DOI: 10.1021/acsmedchemlett.6b00005
Alan G. Olivero, Bruno Alicke, Chudi O. Ndubaku, Cristina Lewis, Emile G. Plise, Jeffrey Wallin, Jim Nonomiya, Jodie Pang, John D. Lesnick, Jonathan Cheong, Joy Drobnick, Kyle Edgar, Lan Wang, Laurent Salphati, Leslie B. Lee, Stephen E. Gould, Steve Sideris, Timothy P. Heffron, Xiaolin Zhang
Keywords: PI3K, kinase inhibitor, blood？brain barrier penetration, CNS, oncology
Abstract:
Full-Text
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