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DOI: 10.3971/j.issn.1000-8578.2016.02.013
Keywords: One Case Report,Platinum Resistance after Neoadjuvant Chemotherapy Interval Debulking Surgery Compared with Primary Debulking Surgery on Patients with Advanced Epithelial Ovarian Carcinoma,P38MAPK Signaling Pathway is Involved in Expression Regulation of uPA Protein in Ovarian Cancer Cells and Tissues,Cathepsin L Promotes Invasion and Migration of Human Ovarian Cancer Cell Line SKOV3,hMSH2 Expression in Ovarian Epithelial Cancer Tissues and Its Relationship with Chemoresistance,Biological Characteristics of Paclitaxel-resistance Ovarian Cancer Cell Lines and Cryopreservation Methods,Bevacizumab in Treatment of Recurrent Ovarian Cancer,Pelvic Inflammatory Disease and Risk of Ovarian Tumor: A Meta-analysis
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摘要 溶血卵磷脂胆碱酰基转移酶1（lysophosphatidylcholine acyltransferase 1, LPCAT1）是一种磷脂酰基代谢酶，可促进磷脂的合成及重构。近年来研究发现LPCAT1在多种肿瘤组织中表达升高，并与肿瘤的恶性程度、分期、分级呈正相关。LPCAT1在肿瘤组织中过表达与前列腺癌、乳腺癌的早期复发呈正相关，在结直肠癌细胞、肝癌细胞中过表达可促进细胞的增殖、迁移、侵袭，是恶性肿瘤早期诊断潜在的生物学标志物和肿瘤治疗的靶点。现对LPCAT1与肿瘤关系的研究进展进行综述
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