仙游县胃癌危险因素的1:2配对病例对照研究
DOI: 10.3971/j.issn.1000-8578.2016.10.014
Keywords: A Meta-analysis,Expression of CLIC4 in Gastric Carcinoma Tissues and Its Relevance to Microsatellite Instability,Efficacy and Safety of Weekly Liposome-paclitaxel or Oxaliplatin Combined with Tegafur on Elderly Advanced Gastric Cancer,Periplocin Extracted from Cortex Periplocae(CPP) Induced Apoptosis of Gastric Cancer Cells MGC-803 Through Lysosomal Pathway,Gastric Cancer Mortality Trend and Difference Decomposition Analysis in Kunshan, Jiangsu Province, 1981-2014,Effect of Ubiquitin-like with PHD and Ring Finger Domain 1 on Invasion and Metastasis of Gastric Cancer and Related Mechanism,Effects of miR-711 on Invasion, Metastasis and Epithelial Mesenchymal Transition of Gastric Cancer Cells MGC-803,Role of p53β Isoform in Inhibitory Effect of rmhTNF Combined with Cisplatin on Human Gastric Cancer Cell Growth,Effect of siRNA Targeting Migration-inducing Protein 7 Gene on Invasion and Migration of Human Gastric Cancer Cells MKN45,Optimization of Housekeeping Gene for Normalization of Quantitative Polymerase Chain Reaction Assay in Gastric Cancer Research,A Case Report of Synchronous Gastric Cancer and Gastric Diffuse Large B-Cell Lymphoma,Development of Peritoneal Carcinomatosis from Gastric Cancer and Current Status of Treatment in China
Abstract:
摘要 目的 探讨仙游县胃癌的危险因素,为当地胃癌的防治提供依据。方法 收集2013年3月—2015年7月在仙游县医院住院并经病理确诊的胃癌患者433例。按仙游县各乡镇胃癌的标化死亡率分成胃癌高、中、低发,乡镇以村为单位随机抽取健康人群,按患者的性别、年龄(±3岁)、居住地进行以人群为基础的1:2配对病例对照研究。应用条件Logistic回归进行单因素及多因素分析,计算OR值及95%可信区间。结果 在控制和考虑其他混杂因素后,进食速度快、喜硬食、常吃腌菜、吸烟、有胃病史、肿瘤家族史、使用农药、对家庭现状不满意等为仙游县胃癌发病的主要危险因素;而常吃蔬菜、食用菌、牛羊肉、海带紫菜及洋葱等则为其保护因素。结论 仙游县胃癌高发与多种因素尤其与当地进食腌菜饮食习惯和大量农药的使用有关,应采取综合措施降低其发病率
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