胃癌腹膜转移的治疗进展
DOI: 10.3971/j.issn.1000-8578.2015.05.019
Keywords: 2 Matched Case-control Investigation on Risk Factors of Gastric Cancer in Xianyou County,Expression of CLIC4 in Gastric Carcinoma Tissues and Its Relevance to Microsatellite Instability,Experiment of Different Administration Sequences of Apatinib and Paclitaxel on Lung Cancer,Knockdown of PKD1 Decreased Sensitivity of Human Salivary Gland Adenoid Cystic Carcinoma Cell Line ACC2 to Paclitaxel,Efficacy and Safety of Weekly Liposome-paclitaxel or Oxaliplatin Combined with Tegafur on Elderly Advanced Gastric Cancer,Periplocin Extracted from Cortex Periplocae(CPP) Induced Apoptosis of Gastric Cancer Cells MGC-803 Through Lysosomal Pathway,Mechanism of Jinlong Capsule Reversing Paclitaxel Resistance of A549 Cells Investigated by System Biology Technology,Gastric Cancer Mortality Trend and Difference Decomposition Analysis in Kunshan, Jiangsu Province, 1981-2014,Effect of Ubiquitin-like with PHD and Ring Finger Domain 1 on Invasion and Metastasis of Gastric Cancer and Related Mechanism,Clinical Investigation on Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy on Patients with Peritoneal Carcinomatosis from Epithelial Ovarian Cancer,Effects of miR-711 on Invasion, Metastasis and Epithelial Mesenchymal Transition of Gastric Cancer Cells MGC-803
Abstract:
摘要 尽管胃癌的治疗策略和方法在不断进步，胃癌患者的预后在逐步改善，但胃癌腹膜转移患者的预后仍非常差，故需不断探索有效的治疗措施和药物。目前全身化疗仍是基础，常用药物有替吉奥（S-1）、紫杉类、铂类等，而腹腔灌注化疗中应用紫杉醇、顺铂、多西他赛等药物也有临床试验显示出一定的疗效。细胞减灭术联合腹腔热灌注化疗可在部分患者中有生存获益甚至获得长期生存。上皮细胞黏附分子EpCAM，腹膜转移普遍表达的靶点，其特异性单抗Catumaxomab可能在胃癌腹膜转移中具有应用前景。本文对胃癌伴腹 膜转移的诊疗进展进行回顾总结
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