%0 Journal Article
%T 胃癌腹膜转移的治疗进展
%A 袁瑛
%A 谭伊诺
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.05.019
%X 摘要 尽管胃癌的治疗策略和方法在不断进步，胃癌患者的预后在逐步改善，但胃癌腹膜转移患者的预后仍非常差，故需不断探索有效的治疗措施和药物。目前全身化疗仍是基础，常用药物有替吉奥（S-1）、紫杉类、铂类等，而腹腔灌注化疗中应用紫杉醇、顺铂、多西他赛等药物也有临床试验显示出一定的疗效。细胞减灭术联合腹腔热灌注化疗可在部分患者中有生存获益甚至获得长期生存。上皮细胞黏附分子EpCAM，腹膜转移普遍表达的靶点，其特异性单抗Catumaxomab可能在胃癌腹膜转移中具有应用前景。本文对胃癌伴腹 膜转移的诊疗进展进行回顾总结
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%U http://www.zlfzyj.com/CN/abstract/abstract8499.shtml