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-  2016 

DNA病毒介导肿瘤发生的表观遗传机制

DOI: 10.3971/j.issn.1000-8578.2016.03.013

Keywords: 病毒,表观遗传,肿瘤发生,甲基化,miRNA,Effects of RNAi Silencing GTPBP4 Gene on Proliferation and Apoptosis of Colon Cancer RKO Cells,Inhibition Effect of Ad-IL24 Combined with Low Dose of 5-Fu on Hepatocarcinoma Cells HepG2 and Its Mechanism,Correlation of ChREBP mRNA Expression and Its CpG Island Methylation in Human Hepatocellular Carcinoma,Relationship of Methylation Status and mRNA Expression of PTEN, RASSF1A in Peripheral Blood with Thyroid Nodule Disease,Recent Advances of Correlation of Mismatch Repair System hMutS, hMutL Variation and Colorectal Cancer,Research Advances of ASPP in Regulating Apoptosis of Tumor Cells,Progress of Epigenetic Modulators in Treatment of Breast Cancer,Significance of Tumor Suppressor Gene TCF21 Promoter Methylation for Diagnosis and Prognosis of Renal Cell Carcinoma,Differences of Clinical Features and Short-term Efficacy Between Diffuse Large B-cell Lymphomas of HIV-infected and Non-HIV-infected Patients,Effect of Ubiquitin-like with PHD and Ring Finger Domain 1 on Invasion and Metastasis of Gastric Cancer and Related Mechanism,TGF-β Induced Abnormal Expression Level of DNA Methyltransferase and Related miRNA During Neonatal Rat Colon Tissue Culture,In vitro Investigation on Effect of Lentiviral Vector-mediated RNA Interference Inhibiting VASH1 Expression on Proliferation and Apoptosis of Human Glioma Cells U-87MG,Expression of Toll-like Receptor 4 and Impact of miR-TLR4 Interference on Biological Activity of HBV-related Hepatocellular Carcinoma Cells,Meta-analysis of Association Between HPV Infection and Disease-free Survival of Oropharyngeal Cancer Patients,miRNA-26a Inhibits Proliferation and Invasion of Breast Cancer Cells Through Downregulating COX-2 Expression

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Abstract:

摘要 许多病毒感染可导致肿瘤发生,这些病毒虽隶属于不同种属,但其进化出的分子干扰机制却有共通之处,即靶向调控与细胞生长和增殖相关的关键蛋白。病毒和宿主之间的相互作用也发生于表观遗传水平。本文对DNA病毒导致癌症发生的表观遗传机制进行综述

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