%0 Journal Article %T DNA病毒介导肿瘤发生的表观遗传机制 %A 宁勇 %A 胡玉倩 %A 谢圣高 %A 郑义 %A 郗娟 %J 肿瘤防治研究 %D 2016 %R 10.3971/j.issn.1000-8578.2016.03.013 %X 摘要 许多病毒感染可导致肿瘤发生,这些病毒虽隶属于不同种属,但其进化出的分子干扰机制却有共通之处,即靶向调控与细胞生长和增殖相关的关键蛋白。病毒和宿主之间的相互作用也发生于表观遗传水平。本文对DNA病毒导致癌症发生的表观遗传机制进行综述 %K 病毒 %K 表观遗传 %K 肿瘤发生 %K 甲基化 %K miRNA %K Effects of RNAi Silencing GTPBP4 Gene on Proliferation and Apoptosis of Colon Cancer RKO Cells %K Inhibition Effect of Ad-IL24 Combined with Low Dose of 5-Fu on Hepatocarcinoma Cells HepG2 and Its Mechanism %K Correlation of ChREBP mRNA Expression and Its CpG Island Methylation in Human Hepatocellular Carcinoma %K Relationship of Methylation Status and mRNA Expression of PTEN %K RASSF1A in Peripheral Blood with Thyroid Nodule Disease %K Recent Advances of Correlation of Mismatch Repair System hMutS %K hMutL Variation and Colorectal Cancer %K Research Advances of ASPP in Regulating Apoptosis of Tumor Cells %K Progress of Epigenetic Modulators in Treatment of Breast Cancer %K Significance of Tumor Suppressor Gene TCF21 Promoter Methylation for Diagnosis and Prognosis of Renal Cell Carcinoma %K Differences of Clinical Features and Short-term Efficacy Between Diffuse Large B-cell Lymphomas of HIV-infected and Non-HIV-infected Patients %K Effect of Ubiquitin-like with PHD and Ring Finger Domain 1 on Invasion and Metastasis of Gastric Cancer and Related Mechanism %K TGF-β Induced Abnormal Expression Level of DNA Methyltransferase and Related miRNA During Neonatal Rat Colon Tissue Culture %K In vitro Investigation on Effect of Lentiviral Vector-mediated RNA Interference Inhibiting VASH1 Expression on Proliferation and Apoptosis of Human Glioma Cells U-87MG %K Expression of Toll-like Receptor 4 and Impact of miR-TLR4 Interference on Biological Activity of HBV-related Hepatocellular Carcinoma Cells %K Meta-analysis of Association Between HPV Infection and Disease-free Survival of Oropharyngeal Cancer Patients %K miRNA-26a Inhibits Proliferation and Invasion of Breast Cancer Cells Through Downregulating COX-2 Expression %U http://www.zlfzyj.com/CN/abstract/abstract8718.shtml