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- 2018
YB1在肿瘤发生发展中的作用研究进展DOI: 10.3971/j.issn.1000-8578.2018.17.1049 Keywords: Take Paneth Cells as an Example,Expression and Clinical Significance of Stem Cells Gene Lgr5 in Esophageal Squamous Cell Carcinoma Tissues,Clinical Significance of Detection of Multiple Serum Cytokines in Gastric Cancer by Liquid Chip Technology,Sulforaphane Suppressed Proliferation of Lung Cancer Stem Cells in vitro,Research Advances of ASPP in Regulating Apoptosis of Tumor Cells,Epigenetic Mechanism of DNA Virus-mediated Carcinogenesis,New Progress on Tumor-associated Macrophages in Tumor Microenvironment,Difference of Self-renewal and Tumorigenicity among Different Breast Cancer Stem Cells Subpopulations Abstract: 摘要 YB1是一种多功能蛋白，广泛参与细胞进程。既往大量研究发现，肿瘤中YB1表达明显升高，其高表达与肿瘤的不良预后和复发密切相关。近几年，针对 YB1影响肿瘤增殖、凋亡、侵袭和化疗耐受等生物学功能的潜在机制研究层出不穷，同时，其对肿瘤干细胞及炎性反应等方面调控作用的研究也逐渐深入。本文就YB1在肿瘤发生发展中的作用研究进展进行综述
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