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DOI: 10.3971/j.issn.1000-8578.2016.05.020
Keywords: 乳腺癌,表观遗传调节剂,DNA甲基转移酶,组蛋白去乙酰化酶,Multi-factors Affect Cardiac Toxicity in Radiotherapy on Left-sided Breast Cancer,Effect of Neoadjuvant Chemotherapy Cycles on Pathologic Complete Response Rate Under Different Estrogen Receptor Status of Breast Cancer,Review of Targeted Therapy for Breast Cancer with BRCA Genes Mutation,Autophagic Cell Death Induced by GANT61 Inhibits Proliferation of Human Breast Cancer Cell Line MCF-7,Effect of Thyroid Hormone Receptor βΔ on Proliferation and Apoptosis of Rat Breast Cancer Cells SHZ-88,Progress on FOXP3 Expression in Breast Cancer Cells,Effect of Hormones from Adrenal Gland on Breast Cancer Metastasis in Mice,Effect of SAHA on Proliferation and Apoptosis of Breast Cancer Cells MDA-MB-435 and Related Mechanism,Analysis E-cad and VEGF Expression in Triple-negative Breast Cancer of Han and Uygur,Regulations and Roles of Breast Cancer Stem Cells,Prediction of Disease Specific Survival Rates by Genes Associated with Relapse of Breast Cancer,Correlation Between Tumor Associated Macrophages and CXCL12 Expression in Different Breast Tissues,Effects of NRP-1 Overexpression on Biological Behaviors of Breast Cancer Cell Lines MDA-MB-231 and SK-BR-3,Effect of Operation Incision Selection on Success rate of Sentinel Lymph Node Biopsy and Subcutaneous Hydrops in Breast Cancer,Expression and Clinical Significance of Artemin Protein in Triple-negative and Nontriple-negative Breast Cancer Tissues
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摘要 近年来，随着对不同类型乳腺癌基因表达谱研究的深入，表观遗传调节剂用来调控乳腺癌异常表达基因而应用于临床。初步结果表明，DNA甲基转移酶和组蛋白去乙酰化酶抑制剂对不同类型的乳腺癌（包括耐药性乳腺癌）均有不同的治疗作用。本文从体外实验研究、临床试验方面，分别对将来可能应用于乳腺癌治疗的表观遗传调节剂进行综述
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