术后化疗对术后淋巴结阳性胸段食管鳞癌患者预后的影响
DOI: 10.3971/j.issn.1000-8578.2018.18.0118
Keywords: A Meta-analysis,Value of 18F-FDG PET/CT in Evaluating Chemotherapeutic Effect of Diffuse Large B Cell Lymphoma Patients with Different CD5 Expression,Advances in Prognostic Value of Peripheral Blood Inflammatory Indexes in Non-small Cell Lung Cancer,Antitumor Efficacy and Mechanisms of Lapatinib in Combination with Cisplatin on Esophageal Squamous Cancer Cells,Expression of Infiltrating NK Cell Surface Receptors in Peripheral Blood and Cancer Tissues of Patients with Esophageal Squamous Cell Carcinoma,Risk Factors of Pathological Upstaging for Patients with Clinical T2N0M0 Esophageal Squamous Cell Carcinoma,Efficacy and Prognostic Factors of Docetaxel Rechallenge on Metastatic Castrationresistant Prostate Cancer Patients,Comparison of Survival and Postoperative Complication of Stage Ⅰb2-Ⅱa2 Cervical Cancer Patients Among Three Kinds of Therapeutic Regimens,Comparison of Survival Status and Related Risk Factors of Esophageal Squamous Cell Carcinoma Patients Between High- and Low-incidence Areas of ESCC,Cholesterol: A Predictor of Risk and Prognosis of Breast Cancer
Abstract:
摘要 目的 分析术后化疗对术后淋巴结阳性胸段食管鳞癌患者预后的影响。方法 回顾性分析419例胸段食管癌患者预后的影响因素。结果 单纯手术患者1、3、5年OS显著低于术后化疗组（χ2=12.802, P=0.000）；而两组患者1、3、5年DFS差异未见统计学意义（χ2=1.159, P=0.282）。多因素分析结果显示，性别、年龄、病变部位、TNM分期、术后化疗和化疗周期数为OS的独立性预后影响因素（P<0.05）；而性别和N分期为DFS的独立性预后影响因素（P<0.05）。分层分析结果显示，相对于单纯手术，术后化疗可以提高男性、年龄≤60岁、胸中下段病变、病变长度≤5.0 cm和ⅢB期患者的OS（P<0.05），而且可以提高男性和年龄≤60岁患者的DFS（P<0.05）。结论 术后淋巴结阳性胸段食管鳞癌患者预后较差，术后化疗可以提高部分患者的预后
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