%0 Journal Article
%T 术后化疗对术后淋巴结阳性胸段食管鳞癌患者预后的影响
%A 刘志坤
%A 李娟
%A 李幼梅
%A 李曙光
%A 李腾
%A 沈文斌
%A 祝淑钗
%A 苏景伟
%A 许金蕊
%A 高红梅
%J 肿瘤防治研究
%D 2018
%R 10.3971/j.issn.1000-8578.2018.18.0118
%X 摘要 目的 分析术后化疗对术后淋巴结阳性胸段食管鳞癌患者预后的影响。方法 回顾性分析419例胸段食管癌患者预后的影响因素。结果 单纯手术患者1、3、5年OS显著低于术后化疗组（χ2=12.802, P=0.000）；而两组患者1、3、5年DFS差异未见统计学意义（χ2=1.159, P=0.282）。多因素分析结果显示，性别、年龄、病变部位、TNM分期、术后化疗和化疗周期数为OS的独立性预后影响因素（P<0.05）；而性别和N分期为DFS的独立性预后影响因素（P<0.05）。分层分析结果显示，相对于单纯手术，术后化疗可以提高男性、年龄≤60岁、胸中下段病变、病变长度≤5.0 cm和ⅢB期患者的OS（P<0.05），而且可以提高男性和年龄≤60岁患者的DFS（P<0.05）。结论 术后淋巴结阳性胸段食管鳞癌患者预后较差，术后化疗可以提高部分患者的预后
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%U http://www.zlfzyj.com/CN/abstract/abstract9250.shtml