肠道菌群与子宫肌瘤的相关性分析
DOI: 10.3971/j.issn.1000-8578.2019.18.0712
Keywords: A Case Report and Literature Review,Expression of TOPⅡα, TP53 and HER2 in Gastric Adenocarcinoma and Their Clinical Significance,Mechanism of Bacterial Biofilm Involved in Colorectal Carcinogenesis,Dissemination Problems of Laparoscopic Uterine Fibroids Morcellation and Its Prevention,Correlation Between Stromal Microenvironment and TLR3 Expression, Prognosis Respectively in Hepatocellular Carcinoma,Preliminary Investigation About Hematokrit Forecast of Chemotherapy Tolerance of Lung Cancer Patients,Effect of Intensity Modulated Radiotherapy Combined with Hormonal Therapy on Fatigue in Patients with Locally Advanced Prostate Cancer,Research Progress of Association of Vitamin D3 and Colorectal Cancer,Cancer-related Fatigue in Advanced Lung Cancer Patients and Its Relationship with Inflammatory Cytokine in Serum,Relationship Between Preoperative Fibrinogen Level and Clinicopathological#br# Characteristics of Colon Cancer,Review on Mechanism of Cytokines in Cancer-related Anemia
Abstract:
摘要 目的 分析女性子宫肌瘤、正常女性肠道中菌群水平，探讨肠道菌群与子宫肌瘤发生的相关性。方法 选取2015年6月至2017年7月海南省妇幼保健院收治的70例女性子宫肌瘤为研究对象，同时选取70例正常体检女性作为对照组，收集两组受检者的粪便，提取其DNA并测定其肠道菌群的数量，比较两组受检者肠道各个菌群水平，并分析肠道菌群与子宫肌瘤发生的相关性。结果 子宫肌瘤组患者细菌总数、乳酸杆菌水平均明显高于对照组，两者比较差异有统计学意义（P<0.05）；双歧杆菌、拟杆菌、梭杆菌和变形杆菌水平均明显低于对照组，两者比较差异有统计学意义（P<0.05）。细菌总数、双歧杆菌和乳酸杆菌水平与子宫肌瘤发生呈正相关（P<0.05），拟杆菌、梭杆菌、变形杆菌水平与子宫肌瘤发生呈负相关（P<0.05）。结论 肠道菌群的数量和菌种与子宫肌瘤的发生存在相关性
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