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-  2015 

2002—2013年上海市浦东新区居民鼻咽癌发病情况及其趋势分析

DOI: 10.3971/j.issn.1000-8578.2015.12.015

Keywords: 鼻咽癌,流行病学,发病率,趋势分析,Trends on Morbidity of Colorectal Cancer Among Residents in Xining City of Qinghai Province, 2009-2014,Comparison of Long-term Efficacy of IMRT plus Concurrent Chemotherapy Versus Neoadjuvant Chemotherapy Followed by IMRT plus Concurrent Chemotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma,Investigation of Dynamic Constituent Ratio Changes of Lung Cancer in Ningxia, 2000-2014,Cancer Incidence and Mortality in Cancer Registries in Hubei Province, 2012,Upper Gastrointestinal Carcinomas Incidence from 2003 to 2012 in Cixian, Hebei Province,Correlation Between Skull Base Invasion and Bone Metastases in Locally Advanced Nasopharyngeal Carcinoma Patients,Tumor Prevalence in Jiang’an District of Wuhan from 2006 to 2013,Application of Geographical Spatial Analysis in Cancer Epidemiology,Epidemiologic Investigation on Mortality Due to Esophagus Cancer in Residents in Xiamen, 2005-2014,Construction of RNAi Targeting CLU Gene and Effect of CLU on Biological Function of Nasopharyngeal Cancer Cells,Research Progress of Neoadjuvant Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma,Effect of 5-Azacytidine on hTERT mRNA Expression and Telomerase Activity in Human Nasopharyngeal Carcinoma Cells,Expression of Annexin A2 in Nasopharyngeal Carcinoma Tissues and Its Clinical Significance,Effects of High Mobility Group Box-1 Protein on Migration and Invasion Ability of Nasopharyngeal Carcinoma Cell Line C666-1 in vitro,Correlation of DNA Repair Gene XRCC1 Single Nucleotide Polymorphism with Sensitivity of Nasopharyngeal Carcinoma Patients to Platinum Chemotherapy

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Abstract:

摘要 目的 分析上海市浦东新区居民2002—2013年鼻咽癌发病情况并预测其发展趋势,为鼻咽癌防治策略提供参考。方法 以2002—2013年上海市浦东新区常住户籍居民为研究对象,按1985年世界标准人口计算鼻咽癌标化发病率(age-standardized rate, ASR),应用Join-point regression program分析率值的年均变化百分比(annual percent change, APC)进行趋势分析。结果 2002—2013年浦东新区新发鼻咽癌1 254例,男女发病人数比为2.63:1,合计粗发病率为3.97/10万人年,世界标化发病率为2.29/10万人年,逐年下降的趋势明显(APC=-5.89%, Z=4.77, P<0.001);男性粗发病率为5.76/10万人年,世界标化发病率为3.36/10万人年,逐年下降的趋势明显(APC=-6.19%, Z=4.73, P<0.001);女性粗发病率为2.18/10万人年,世界标化发病率为1.25/10万人年,逐年下降的趋势明显(APC=-5.56%,Z=3.87, P=0.003); 居民鼻咽癌发病率在65~69岁时达到最高峰(11.52/10万人年);男性鼻咽癌发病率在70~74岁时达到最高峰(18.56/10万人年) ; 女性鼻咽癌发病率在60~64岁时达到最高峰(6.17/10万人年)。结论 浦东新区鼻咽癌发病率近年来呈明显下降趋势, 相关部门应针对重点人群积极开展鼻咽癌病因学研究并应用早期诊断技术以进一步降低其发病率

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