%0 Journal Article
%T 2002—2013年上海市浦东新区居民鼻咽癌发病情况及其趋势分析
%A 孙乔
%A 张美玉
%A 李小攀
%A 李晓莉
%A 杨琛
%A 王莉红
%A 郑晓
%A 郝莉鹏
%J 肿瘤防治研究
%D 2015
%R 10.3971/j.issn.1000-8578.2015.12.015
%X 摘要 目的 分析上海市浦东新区居民2002—2013年鼻咽癌发病情况并预测其发展趋势，为鼻咽癌防治策略提供参考。方法 以2002—2013年上海市浦东新区常住户籍居民为研究对象，按1985年世界标准人口计算鼻咽癌标化发病率（age-standardized rate, ASR），应用Join-point regression program分析率值的年均变化百分比（annual percent change, APC）进行趋势分析。结果 2002—2013年浦东新区新发鼻咽癌1 254例，男女发病人数比为2.63:1，合计粗发病率为3.97/10万人年，世界标化发病率为2.29/10万人年，逐年下降的趋势明显（APC=-5.89%, Z=4.77, P<0.001）；男性粗发病率为5.76/10万人年，世界标化发病率为3.36/10万人年，逐年下降的趋势明显（APC=-6.19%, Z=4.73, P<0.001）；女性粗发病率为2.18/10万人年，世界标化发病率为1.25/10万人年，逐年下降的趋势明显（APC=-5.56%,Z=3.87, P=0.003）； 居民鼻咽癌发病率在65~69岁时达到最高峰（11.52/10万人年）；男性鼻咽癌发病率在70~74岁时达到最高峰（18.56/10万人年） ； 女性鼻咽癌发病率在60~64岁时达到最高峰（6.17/10万人年）。结论 浦东新区鼻咽癌发病率近年来呈明显下降趋势, 相关部门应针对重点人群积极开展鼻咽癌病因学研究并应用早期诊断技术以进一步降低其发病率
%K 鼻咽癌
%K 流行病学
%K 发病率
%K 趋势分析
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%U http://www.zlfzyj.com/CN/abstract/abstract8663.shtml