核仁小分子RNAs与癌症的研究进展
DOI: 10.3971/j.issn.1000-8578.2015.01.021
Keywords: 核仁小分子RNAs,癌症,癌症诊断与治疗,Pathways of Lipid Metabolism and Their Associated Disorders in Cancer,Effect of Intensity Modulated Radiotherapy Combined with Hormonal Therapy on Fatigue in Patients with Locally Advanced Prostate Cancer,Advances in Relationship Between Nedd4-like Family of E3 Ubiquitin Ligases and Cancer,Cancer-related Fatigue in Advanced Lung Cancer Patients and Its Relationship with Inflammatory Cytokine in Serum,Discovery Approach and Economic Burden of Six Kinds of Common Cancers Patients in Beijing,Relationship between Age,Gender and Symptoms in Advanced Cancer Patients,Experimental of Influence of Roxithromycin on Cancer Cachexia,Survey of Cancer Pain and Its Treatment
Abstract:
摘要 核仁小分子RNAs (small nucleolar RNAs, snoRNAs) 是一类小分子非编码RNA，其广泛分布于真核生物的细胞核核仁中。近年来，越来越多的研究证明snoRNAs的失调与癌症相关。snoRNAs可能作为抑制基因或原癌基因参与到癌症发生与发展的过程中。并且，snoRNAs相关的基因印记、人端粒末端转移酶以及核糖体病变也被发现与癌症的发生有关。另外，snoRNAs在癌症的诊断与治疗中具有潜在的应用。本文简要总结了snoRNAs的新功能以及snoRNAs在癌症诊断与治疗中潜在应用的研究进展
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