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-  2015 

蛋白质组学在恶性胸腔积液研究中的应用现状及进展

DOI: 10.3971/j.issn.1000-8578.2015.03.017

Keywords: 蛋白质组学,恶性胸腔积液,生物标志物,Progress of Relationships of Calprotectin with Tumours,Screening of Potential Proteins Associated with Carboplatin-resistance in Advanced Ovarian Serous Adenocarcinoma Tissues Using iTRAQ Technology,Review on Researches of TFF3 as Tumor Biomarker,MicroRNAs Expression in Benign and Malignant Pleural Effusion,Recent Progress of microRNA as Colorectal Cancer Clinical Biomarker,Correlation of Dynamic Changes of Candidate Plasma Proteins Expression with Development of Cervical Carcinogenesis in Uyghur Women,Clinical Characteristics and Prognostic Factors in Breast Cancer with Malignant Pleural Effusion,Research for Proteomics Discrepancies between Osteosarcoma and Normal Bone Tissue,Expression and Clinical Significance of microRNA-31 in Primary Lung Cancer Tumor Tissues,Effects of Intrathoracic DC-CIK Treatment and Chemotherapy on Immune Indexes in Malignant Pleural Effusion,Serum Protein Fingerprint Diagnoic Patterns was Established by MALDI-TOF MS for Human Esophagial Carcinoma,Role of Quantitative Proteomic Strategy by Laser Capture Microdissection Combined with Acetylation Stable Isotope Labeling in Colorectal Cancer,Cisplatin Combined with Interleukin-2 to Treat Malignant Pleural Effusion

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Abstract:

摘要 蛋白质组学的研究对象是生命活动的执行者——蛋白质,而恶性胸腔积液中富含蛋白质,尤其是组织特异性、肿瘤相关性的蛋白,所以通过蛋白质组学研究恶性胸腔积液对于认识其蛋白谱、找出疾病相关的生物标志物、发现病因有重要意义。本文主要从组成蛋白质组学及比较蛋白质组学两方面,对近年来蛋白质组学在恶性胸腔积液中的研究进行综述

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