%0 Journal Article %T 蛋白质组学在恶性胸腔积液研究中的应用现状及进展 %A 刘晓晴 %A 杨琳 %A 许晶 %J 肿瘤防治研究 %D 2015 %R 10.3971/j.issn.1000-8578.2015.03.017 %X 摘要 蛋白质组学的研究对象是生命活动的执行者——蛋白质,而恶性胸腔积液中富含蛋白质,尤其是组织特异性、肿瘤相关性的蛋白,所以通过蛋白质组学研究恶性胸腔积液对于认识其蛋白谱、找出疾病相关的生物标志物、发现病因有重要意义。本文主要从组成蛋白质组学及比较蛋白质组学两方面,对近年来蛋白质组学在恶性胸腔积液中的研究进行综述 %K 蛋白质组学 %K 恶性胸腔积液 %K 生物标志物 %K Progress of Relationships of Calprotectin with Tumours %K Screening of Potential Proteins Associated with Carboplatin-resistance in Advanced Ovarian Serous Adenocarcinoma Tissues Using iTRAQ Technology %K Review on Researches of TFF3 as Tumor Biomarker %K MicroRNAs Expression in Benign and Malignant Pleural Effusion %K Recent Progress of microRNA as Colorectal Cancer Clinical Biomarker %K Correlation of Dynamic Changes of Candidate Plasma Proteins Expression with Development of Cervical Carcinogenesis in Uyghur Women %K Clinical Characteristics and Prognostic Factors in Breast Cancer with Malignant Pleural Effusion %K Research for Proteomics Discrepancies between Osteosarcoma and Normal Bone Tissue %K Expression and Clinical Significance of microRNA-31 in Primary Lung Cancer Tumor Tissues %K Effects of Intrathoracic DC-CIK Treatment and Chemotherapy on Immune Indexes in Malignant Pleural Effusion %K Serum Protein Fingerprint Diagnoic Patterns was Established by MALDI-TOF MS for Human Esophagial Carcinoma %K Role of Quantitative Proteomic Strategy by Laser Capture Microdissection Combined with Acetylation Stable Isotope Labeling in Colorectal Cancer %K Cisplatin Combined with Interleukin-2 to Treat Malignant Pleural Effusion %U http://www.zlfzyj.com/CN/abstract/abstract8450.shtml