Background:Chronic kidney disease patients are at a greater risk for nephropathy requiring dialysis after percutaneous coronary intervention. Such patients are usually deferred due to fear of “Renalism”.？Objectives This study assesses the outcome of Low dose contrast protocol during PCI in CKD patients whose e-GFR < 60 ml/min/1.72m and investigates a safety margin for contrast use in these high-risk categories.？Methods: Patients were into three groups according to CV/e-GFR ratio: Group (A) low-dose: CV/e-GFR ratio <2.0 Group (B) medium-dose: CV/e-GFR ratio > 2.0 and < MACD (5× bodyweight\s.creatinine). Group (C) high-dose: CV/e-GFR ratio>MACD. Results: A total of 73 patients were enrolled. Average age was 54 ± 8 years,81.4% were male and 18.6% were females and 52% were diabetic. Mean baseline e-GFR was 40 ± 8.0 ml/min/1.73m2. Contrast Volume used in group A was (58.26 ± 15.05) (n = 24), in group B (109.42 ± 17.11)
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