%0 Journal Article %T Clinical Outcome of Low Dose Contrast during Percutaneous Coronary Intervention in Patients with Moderate to Severe Kidney Impairment %A Wassam Eldin Elshafey %A Walaa Farid Abdel Aziz %A Ahmed Magdy Kamal Eldin %A Mohamed Mahmoud Khattab %J World Journal of Cardiovascular Diseases %P 781-795 %@ 2164-5337 %D 2019 %I Scientific Research Publishing %R 10.4236/wjcd.2019.911070 %X Background: Chronic kidney disease patients are at a greater risk for nephropathy requiring dialysis after percutaneous coronary intervention. Such patients are usually deferred due to fear of ¡°Renalism¡±. Objectives This study assesses the outcome of Low dose contrast protocol during PCI in CKD patients whose e-GFR < 60 ml/min/1.72 m and investigates a safety margin for contrast use in these high-risk categories. Methods: Patients were into three groups according to CV/e-GFR ratio: Group (A) low-dose: CV/e-GFR ratio <2.0 Group (B) medium-dose: CV/e-GFR ratio > 2.0 and < MACD (5¡Á bodyweight\s.creatinine). Group (C) high-dose: CV/e-GFR ratio > MACD. Results: A total of 73 patients were enrolled. Average age was 54 ¡À 8 years,81.4% were male and 18.6% were females and 52% were diabetic. Mean baseline e-GFR was 40 ¡À 8.0 ml/min/1.73m². Contrast Volume used in group A was (58.26 ¡À 15.05) (n = 24), in group B (109.42 ¡À 17.11)