超重对行胃癌根治术患者近期临床疗效的影响
Impact of overweight on short-term outcomes of radical gastrectomy on gastric cancer patients

摘要：目的 探讨超重对于胃癌根治术近期疗效的影响。方法 回顾性收集2009年1月至2012年12月于我科行胃癌根治术的患者166例(超重组102例，非超重组64例)，比较两组患者术中、术后以及近期生存情况。结果 超重组手术时间明显长于非超重组[(237.70±59.16)min vs. (210.55±54.49)min，P<0.05))，术中出血量亦明显高于非超重组[(346.41±223.63)mL vs. (276.77±155.46)mL，P<0.05)]；两组的术中总淋巴结清扫数、肛门排气时间、进食时间、术后住院时间以及术后并发症的差异均无统计学意义。超重组和非超重组的3年生存率分别为76.8%和65.1%，差异无统计学意义(P>0.05)。结论 超重会延长手术时间和增加术中的出血量，但不会影响手术的近期疗效。
ABSTRACT: Objective To investigate the impact of overweight on short-term outcomes of radical gastrectomy on gastric cancer (GC). Methods We collected retrospectively the clinical data of 166 GC patients (102 overweight and 64 non-overweight ones) who had undergone radical resection in our department from January 2009 to December 2012. We then compared the two groups in intraoperative and postoperative parameters as well as short-term survival rate. Results The operation time of overweight GC patients was longer than that of non-overweight GC ones (237.70±59.16)min vs. (210.55±54.49)min (P<0.05); the intraoperative blood loss of overweight GC patients was more than that of non-overweight GC patients (346.41±223.63)mL vs. (276.77±155.46)mL (P<0.05). There were no significant differences between the two groups in the number of retrieved lymph nodes, the first flatus time, the first time to have liquid diet, postoperative hospitalization time, postoperative complications, or postoperative 3-year overall survival rate (76.8% and 65.1%) (all P>0.05). Conclusion Overweight is associated with longer operation time and more intraoperative blood loss, but it does not affect the short-term outcomes of the operation