Zuo XR,Wang Q,Cao Q,et al.Nicorandil prevents right ventrivular remodeling by inhibiting apoptosis and lowering pressure overload in rats with pulmonary arterial hypertension[J].Plos One,2012,7(9):e44485.
[2]
Sun Y,Zhang J,Zhang JQ,et al.Local angiotensinⅡand transforming growth factorβ1in renal fibrosis of rats[J].Hypertension,2000,35(5):1 078-1 084.
[3]
Aragno M,Mastrocola R,Alloatti G,et al.Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats[J].Endocrinology,2008,149(1):380-388.
[4]
Nakae I,Takaoka A,Mitsunami K,et al.Cardioprotective effects of nicorandil in rabbits anaesthetized with halothane:potentiation of ischaemic preconditioning via KATP channels.Clinical and Experimental Pharmacology and Physiology,2000,27:810-817.
[5]
Zhang XM,Shi PH,Cao SH,et al.Expression changes of transforming growth factor-beta1 and thrombospondin-1in cavernous tissues of diabetic rats[J].Urologia Internationlis,2010,84(2):221-225.
[6]
Garside SA,Harlow CR,Hillier SG,et al.Thrombospondin-1inhibits angiogenesis and promotes follicular atresia in a novel in vitro angiogenesis assay[J].Endocrinology,2010,151(3):1 280-1 289.
[7]
Belmadani S,Bernal J,Wei CC,et al.A thrombospondin-1antagonist of transforming growth factor-βactivation blocks cardiomyopathy in rats with diabetes and elevated angiontensinⅡ[J].The American Journal of Pathology,2007,171:777-789.
[8]
Lu C,Minatoguchi S,Arai M,et al.Nicorandil improves post-ischemic myocardial dysfunction in association with opening the mitochondrial KATP channels and decreasing hydroxyl radicals in isolated rat hearts[J].Circ J,2006,70:1 650-1 654.
[9]
Colombo G,Margosio B,Ragona L,et al.Non-peptidic thrombospondin-1mimics as fibroblast growth factor-2inhibitors.An integrated strategy for the development of new antiangiogenic compounds[J].Journal of Biological Chemistry,2010,285(12):8 733-8 742.
[10]
Serizawa K,Yogo K,Aizawa K,et al.Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalization of NADPH oxidase and nitric oxide synthase in streptozocin diabetic rats.Cardiovasc Diabetol,2011,10:105-110.
