甲状腺癌信号通路的研究进展

甲状腺癌是内分泌系统中最常见的恶性肿瘤,大部分患者在行甲状腺根治切除术后,联合I131放射治疗及药物化疗之后能够得到长期的生存率,但仍然有大约20%的患者,可能由于对化疗药物以及放射治疗不敏感,导致癌灶周围或者远处组织的转移。本文就甲状腺癌相关通路研究作一综述。
Thyroid cancer is the most common endocrine malignancy. Most patients are managed successfully with a combination of radioiodine and levothyroxine treatment following complete thyroidectomy, while still nearly 20% patients will develop a local or distant recurrence, perhaps because of insensitivity to conventional chemo-and radio-therapy. This article reviews the recent progress on signal pathways in thyroid cancer