%0 Journal Article
%T 甲状腺癌信号通路的研究进展
%A 李登峰综述
%A 房林审校
%J 同济大学学报(医学版)
%D 2015
%R 10.16118/j.1008-0392.2015.05.027
%X 甲状腺癌是内分泌系统中最常见的恶性肿瘤,大部分患者在行甲状腺根治切除术后,联合I131放射治疗及药物化疗之后能够得到长期的生存率,但仍然有大约20%的患者,可能由于对化疗药物以及放射治疗不敏感,导致癌灶周围或者远处组织的转移。本文就甲状腺癌相关通路研究作一综述。</br>Thyroid cancer is the most common endocrine malignancy. Most patients are managed successfully with a combination of radioiodine and levothyroxine treatment following complete thyroidectomy, while still nearly 20% patients will develop a local or distant recurrence, perhaps because of insensitivity to conventional chemo-and radio-therapy. This article reviews the recent progress on signal pathways in thyroid cancer
%K 甲状腺肿瘤 丝裂原活化蛋白激酶信号通路 磷脂酰肌醇激酶-蛋白激酶信号通路&lt
%K /br&gt
%K thyroid carcinoma MAPK signal pathways PI3K-AKT signal pathways
%U http://tjyxxb.cnjournals.cn/ch/reader/view_abstract.aspx?file_no=20150527&flag=1