Ag(Ⅰ)催化的分子内氢胺化-Michael加成串联反应

通过甘氨酸酯衍生的炔胺化合物在Ag(Ⅰ)催化下发生分子内氢胺化-Michael加成串联反应，在较为温和的条件下合成了多取代的3,4-二氢吡咯结构.该方法为合成多取代的3,4-二氢吡咯结构提供了一种高效简便的途径.
Abstract：Starting from amino alkynes derived from glycine esters, silver(Ⅰ) catalyst was employed for a tandem intramolecular hydroamination/Michael addition process under mild conditions. This reaction provides an efficient approach to substituted 3,4-dihydro-2H-pyrroles