Background: Mother
to child transmission (MTCT) of HIV constitutes a major source of new pediatric
infections in Cameroon. Objective: The aim of this implementation research
was to assess outcomes and effectiveness of providing life-long antiretroviral therapy
(ART) for HIV-positive pregnant and breastfeeding women (Option B+). Methods: From October 2013 to July 2014, HIV-positive pregnant and breastfeeding women, not
on antiretroviral (ARV) prophylaxis and ART, were recruited from 22 purposefully
selected health facilities in the Northwest and Southwest regions for a prospective,
observational cohort evaluation. Option B+ was offered to participants and outcome
indicators were measured. Results: Out of 680 women eligible for this assessment,
669 (98%) were initiated on Option B+. Retention-in-care was 90% (95% CI, 87.85-92.61) and 79% (95% CI, 75.20-81.88), and loss to follow
up (LTFU) was 7% (95% CI: 4.95-
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