%0 Journal Article
%T Outcome Evaluation of Early Implementation of Option B+ in Cameroon: A Prospective Cohort Observational Survey in the Northwest and Southwest Regions
%A Pius Tih Muffih
%A Edouard Katayi Tshimwanga
%A Andrew Abutu
%A Lem Edith Abongwa
%A Jacques Chirac Awa
%A Pascal Nji Atanga
%A Felix Desembuin
%A Eveline Mboh Khan
%A Kuni Esther Bonje
%A Nshom Emmanuel
%A Ebeny Francois Temgbait Chimoun
%A Thomas Welty
%A Gladys Tayong Fosah
%A Jennifer Lim
%A Dana Duncan
%A Leah Petit
%A Gilbert Tene
%A Jembia Mosoko
%A Omotayo Bolu
%J World Journal of AIDS
%P 90-104
%@ 2160-8822
%D 2018
%I Scientific Research Publishing
%R 10.4236/wja.2018.83008
%X <span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">Background</span></b></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">: Mother
to child transmission (MTCT) of HIV constitutes a major source of new pediatric
infections in Cameroon. </span><b><span style=\"font-family:Verdana;\">Objective:</span></b><span style=\"font-family:Verdana;\"> The aim of this implementation research
was to assess outcomes and effectiveness of providing life-long antiretroviral therapy
(ART) for HIV-positive pregnant and breastfeeding women (Option B+). </span><b><span style=\"font-family:Verdana;\">Methods:</span></b><span style=\"font-family:Verdana;\"> From October 2013 to July 2014, HIV-positive pregnant and breastfeeding women, not
on antiretroviral (ARV) prophylaxis and ART, were recruited from 22 purposefully
selected health facilities in the Northwest and Southwest regions for a prospective,
observational cohort evaluation. Option B+ was offered to participants and outcome
indicators were measured. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> Out of 680 women eligible for this assessment,
669 (98%) were initiated on Option B+. Retention-in-care was 90% (95% CI, 87.85</span></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">-</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">92.61) and 79% (95% CI, 75.20</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">-</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">81.88), and loss to follow
up (LTFU) was 7% (95% CI: 4.95</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">-</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span
%K Option B+
%K Implementation Research
%K Prevention of Mother to Child HIV Transmission
%K HIV Exposed Infants
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=87446