Influence
of dosimetric considerations in evaluating second cancer risks in prostate
cancer. Material and methods: Fifteen patients in this study suffering from
early stage of prostate cancer, each patient underwent three plans:1) Three-dimensional
conformal radiation therapy (3DCRT), 2) Rotation therapy (Arc
therapy), and 3) intensity-modulated
radiation therapy (IMRT) plan. Estimate secondary metastasis risk models:
Excess Relative Risk (ERR) and Excess absolute risk (EAR) based on age of
exposure by taking dosimetry data from Dose Volume Histograms (DVHs) to
calculate risk models. Result: The second cancer risk models (ERR and EAR) for
organs at risk OARs decrease with increasing age of exposure for 3D-CRT, ARC
and IMRT and there is no significant difference for ERR and EAR model for
developing second
cancer risk in 3D-CRT, ARC and IMRT.
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