%0 Journal Article
%T Influence of Dosimetric Considerations in Evaluating Second Cancer Risks in Prostate Cancer
%A Raghda A. Elgendy
%A Wahib M. Attia
%A Ehab M. Attalla
%A Mostafa A. lnaggar
%J International Journal of Medical Physics,Clinical Engineering and Radiation Oncology
%P 203-213
%@ 2168-5444
%D 2018
%I Scientific Research Publishing
%R 10.4236/ijmpcero.2018.72018
%X Influence
of dosimetric considerations in evaluating second cancer risks in prostate
cancer. Material and methods: Fifteen patients in this study suffering from
early stage of prostate cancer, each patient underwent three plans<span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">:</span></span></span><span><span><span style=\"font-family:;\" \"=\"\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">1)</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> Three-dimensional
conformal radiation therapy (3DCRT), </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">2)</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> Rotation therapy (Arc
therapy)</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">,</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> and </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">3)</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> intensity-modulated
radiation therapy (IMRT) plan. Estimate secondary metastasis risk models:
Excess Relative Risk (ERR) and Excess absolute risk (EAR) based on age of
exposure by taking dosimetry data from Dose Volume Histograms (DVHs) to
calculate risk models. Result: The second cancer risk models (ERR and EAR) for
organs at risk OARs decrease with increasing age of exposure for 3D-CRT, ARC
and IMRT and there is no significant difference for ERR and EAR model for
develop</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">ing</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> second
cancer risk in 3D-CRT, ARC and IMRT</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">.</span></span></span>
%K Prostate Cancer
%K Second Cancer Risks
%K 3DCRT
%K Rotational Arc and IMRT
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=84879