Cu(OTf)2(Py)4 mediated radiofluorination of the boronate esters of
ethyl benzoyl and phthaloylglycinates (11 and 16) using 10 mol% of the copper
complex following the literature procedure did not provide the fluorinated
products. However, the addition of Cu(OTf)2resulted in the radio-fluorination of the boronate esters 11
and 16 to obtain ethyl 4-[18F]fluorobenzoyl glycinate, 17, (48%) and ethyl 3-[18F]phthaloylglycinate (41%) respectively.
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