α-calcium sulfate hemihydrate (α-HH) is known to be suitable for application as bone void filler.
High percentage of α-HH is obviously
needed for medical applications, especially for implantation. Three commercially
available calcium sulfate dihydrates (DH, CaSO4·2H2O) with different sizes and
surface morphologies were used as starting materials to synthesize high
percentage α-HH via a hydrothermal
method. The median particle sizes of the three types of DH were 946.7 μm, 162.4 μmand 62.4 μm, respectively. They were named as DH-L, DH-M and DH-S in this paper. The particle size
distribution, morphology and phase composition of the raw materials were evaluated
before synthesis. SEM results revealed that DH-L consisted of irregular large particles,
while DH-M and DH-S werecomposed of plate-like particles
with some small ones. High percentage HH can be obtained with proper synthesis parameters by hydrothermal
method, specifically, 105°C/90 min for DH-L (achieving
98.8% HH), 105°C/30 min for DH-M
(achieving 96.7% HH) and 100
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