%0 Journal Article
%T Preparation of High Percentage <i>¦Á</i>-Calcium Sulfate Hemihydrate via a Hydrothermal Method
%A Le Fu
%A Wei Xia
%A Torbj£¿rn Mellgren
%A Mikael Moge
%A H£¿kan Engqvist
%J Journal of Biomaterials and Nanobiotechnology
%P 36-49
%@ 2158-7043
%D 2017
%I Scientific Research Publishing
%R 10.4236/jbnb.2017.81003
%X ¦Á-calcium sulfate hemihydrate (¦Á-HH) is known to be suitable for application as bone void filler.
High percentage of ¦Á-HH is obviously
needed for medical applications, especially for implantation. Three commercially
available calcium sulfate dihydrates (DH, CaSO4¡¤2H2O) with different sizes and
surface morphologies were used as starting materials to synthesize high
percentage ¦Á-HH via a hydrothermal
method. The median particle sizes of the three types of DH were 946.7 ¦Ìm, 162.4 ¦Ìm and 62.4 ¦Ìm, respectively. They were named as DH-L, DH-M and DH-S in this paper. The particle size
distribution, morphology and phase composition of the raw materials were evaluated
before synthesis. SEM results revealed that DH-L consisted of irregular large particles,
while DH-M and DH-S were composed of plate-like particles
with some small ones. High percentage HH can be obtained with proper synthesis parameters by hydrothermal
method, specifically, 105 °C/90 min for DH-L (achieving
98.8% HH), 105°C/30 min for DH-M
(achieving 96.7% HH) and 100