Li W, Li Z, Yang J, et al. Production of glutathione using a bifunctio-nal enzyme encoded by gshF from Streptococcus thermophilus expressed in Escherichia coli[J]. Journal of Biotechnology, 2011, 154(4)：261-268.
[4]
Gopal S, Borovok I, Ofer A, et al. A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis[J]. Journal of Bacteriology, 2005, 187(11)：3839-3847.
[5]
Liang G, Liao X, Du G, et al. Optimization of amino acids addition for efficient production of glutathione in Candida utilis[J]. Biochemical Engineering Journal, 2008, 41(3)：234-240.
[6]
Fei L, Wang Y, Chen S. Improved glutathione production by gene expression in Pichia pastoris[J]. Bioprocess and Biosystems Engineering, 2009, 32(6)：729-735.
[7]
Meister A, Anderson M. Glutathione[J]. Annual Review of Biochemistry, 1983, 52(1)：711-760.
[8]
Sies H. Glutathione and its role in cellular functions[J]. Free Radical Biology and Medicine, 1999, 27(9)：916-921.
[9]
Liao X, Shen W, Chen J, et al. Improved glutathione production by gene expression in Escherichia coli[J]. Letters in Applied Microbiology, 2006, 43(2)：211-214.
Janowiak B, Griffith O. Glutathione synthesis in Streptococcus agalactiae：one protein accounts for γ-glutamylcysteine synthetase and glutathione synthetase activities[J]. Journal of Biological Chemistry, 2005, 280(12)：11829-11839.
[12]
Alfafara C, Kanda A, Shioi T, et al. Effect of amino acids on glutathione production by Saccharomyces cerevisiae[J]. Applied Microbiology and Biotechnology, 1992, 36(4)：538-540.
[13]
Wen S, Zhang T, Tan T. Utilization of amino acids to enhance glutathione production in Saccharomyces cerevisiae[J]. Enzyme and Microbial Technology, 2004, 35(6)：501-507.
[14]
Li Y, Chen J, Mao Y, et al. Effect of additives and fed-batch culture strategies on the production of glutathione by recombinant Escherichia coli[J]. Process Biochemistry, 1998, 33(7)：709-714.
[15]
Wang Z, Tan T, Song J. Effect of amino acids addition and feedback control strategies on the high-cell-density cultivation of Saccharomyces cerevisiae for glutathione production[J]. Process Biochemistry, 2007, 42(1)：108-111.
[16]
Alfafara C, Miura K, Shimizu H, et al. Cysteine addition strategy for maximum glutathione production in fed-batch culture of Saccharomyces cerevisiae[J]. Applied Microbiology and Biotechnology, 1992, 37(2)：141-146.
[17]
Wen S, Zhang T, Tan T. Maximizing production of glutathione by amino acid modulation and high-cell-density fed-batch culture of Saccharomyces cerevisiae[J]. Process Biochemistry, 2006, 41(12)：2424-2428.
[18]
Liang G, Liao X, Du G, et al. Elevated glutathione production by adding precursor amino acids coupled with ATP in high cell density cultivation of Candida utilis[J]. Journal of Applied Microbiology, 2008, 105(5)：1432-1440.
