Meister A, Andersen ME. Glutathione[J]. Ann Rev Biochem, 1983, 52：711-760. [2] Li Y, Wei G, Chen J. Glutathione：a review on biotechnological production[J]. Appl Microbiol Biotechnol, 2004, 66（3）：233-242. [3] Yoshida K, Hariki T, Inoue H, et al. External skin preparation for whitening：JP, 2002284664[P]. 2002. [4] Liang GB, Du GC, Chen J. A novel strategy of enhanced glutathione production in high cell density cultivation of Candida utilis—cysteine addition combined with dissolved oxygen controlling[J]. Enzyme Microb Technol, 2008, 42（3）：284-289. [5] Tong QY, Wang GC, Du GC, et al. Effect of feeding method on production of glutathione by Saccharomyces cerevisiae[J]. J Ind Microbiol, 2003, 33（1）：19-22. [6] Alfafara CG, Miura K, Shimizu H, et al. Fuzzy control of ethanol concentration and its application to maximum glutathione production in yeast fedbatch culture[J]. Biotechnol Bioeng, 1993, 41（4）：493-501. [7] Alfafara CG, Kanda A, Shioi T, et al. Effect of amino acids on glutathione production by Saccharomyces cerevisiae[J]. Appl Microbiol Biotechnol, 1992, 36（4）：538-540. [8] Alfafara CG, Miura K, Shimizu H, et al. Cysteine addition strategy for maximum glutathione production in fed-batch culture of Saccharomyces cerevisiae[J]. Appl Microbiol Biotechnol, 1992, 37（2）：141-146. [9] Wen SH, Zhang T, Tan TW. Utilization of amino acids to enhance glutathione production in Saccharomyces cerevisiae[J]. Enzyme and Microbial Technology, 2004, 35（6-7）：501-507. [10] Wen SH, Zhang T, Tan TW. Optimization of the amino acid compo-sition in glutathione fermentation[J]. Process Biochemistry, 2005, 40（11）：3474-3479. [11] Ohtake Y, Watanabe K, Tezuka H, et al. The expression of the γ-glutamylcysteine synthetase gene of Escherichia coli B in Saccharomyces cerevisiae[J]. Agric Biol Chem, 1988, 52（11）：2753-2762. [12] Christine LH, Ulf S. Recombinant yeast for manufacture of glutathione：Euro, 300168[P]. 1989. [13] Fan XY, He XP, Guo XN, et al. Increasing glutathione formation by functional expression of the γ-glutamylcysteine synthetase gene in Saccharomyces cerevisiae[J]. Biotechnology Letters, 2004, 26（5）：415-417. [14] 艾丽静, 饶志明, 诸葛健, 等. GSH1基因的克隆及其在巴斯德毕赤氏酵母中的表达[J].应用与环境生物学报, 2007, 13（2）：257-260. [15] Meister A. Glutathione metabolism and its selective modifica-tion[J]. J Biol Chem, 1988, 263（33）：17205-17208. [16] 陈书霞, 王晓武, 房玉林.单菌落PCR法直接快速鉴定重组克隆[J].微生物学通报, 2006, 33（3）：52-56. [17] Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning：A Laboratory Manual[M]. 2nd ed. New York：Cold Spring Harbor Laboratory Press, 1989. [18] Li TK. The glutathione and thiol content of mammalian spermatozoa and seminal plasma[J]. Biol Reprod, 1975, 12（5）：641-646.
