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化工进展  2015 

有机相中脂肪酶催化转酯化反应动力学拆分左旋帕罗醇

, PP. 116-120

Keywords: 有机相,,转酯化,动力学拆分,左旋帕罗醇

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Abstract:

研究了在有机相中脂肪酶催化转酯化反应动力学拆分左旋帕罗醇,考察了酶种类、溶剂、酰基供体、温度、底物与酰基供体摩尔比等因素对反应的影响。结果表明以Novozym435为催化剂,在30℃下,以乙腈为反应溶剂,乙酸乙烯酯为酰基供体,底物浓度40mmol/L及其与酰基供体摩尔比为18时,反应8h后,底物转化率为48.1%,ees为53.3%,E值为6.20。

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