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冷冻干燥参数对塌陷温度的影响分析

, PP. 126-129

Keywords: 冷冻干燥,塌陷温度,冻干显微镜,玻璃化转变,差示扫描量热法

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Abstract:

利用冻干显微镜研究了溶液冷冻干燥过程中降温速率、升华压力、溶液质量分数对干燥层塌陷温度Tc的影响,采用差示扫描量热法测量了溶液的玻璃化转变温度T′g。实验结果表明,对于10%蔗糖/水二元溶液,降温速率虽然能改变冰晶大小,但对塌陷温度没有明显的影响。而对于10%叔丁醇/10%蔗糖/水三元溶液,T′g和Tc均随降温速率增大而显著降低。压力对塌陷温度影响不大。溶液质量分数不同,塌陷温度略有变化。

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