Al-Khateeb J M, Al-Khateeb A J. Research on psychosocial aspects of epilepsy in Arab countries: a review of literature[J]. Epilepsy Behav, 2014, 31: 256-262. [2]Bakker J, Basedow F J, Dekker A D,et al. Phosphorylation of AMPA-type glutamate receptors: the trigger of epileptogenesis?[J]. J Neurosci, 2013, 33(14): 5879-5880. [3]Engel J Jr. Mesial temporal lobe epilepsy: what have we learned?[J]. Neuroscientist, 2001, 7(4): 340-352. [4]Badawy R A, Freestone D R, Lai A,et al. Epilepsy: Ever-changing states of cortical excitability[J]. Neuroscience, 2012, 222: 89-99. [5]Lu W, Shi Y, Jackson A C,et al. Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach[J]. Neuron, 2009, 62(2): 254-268. [6]Rajasekaran K, Joshi S, Kozhemyakin M,et al. Receptor trafficking hypothesis revisited: plasticity of AMPA receptors during established status epilepticus[J]. Epilepsia, 2013, 54(Suppl 6): 14-16. [7]Serova L I, Laukova M, Alaluf L G,et al. Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress[J]. Behav Brain Res, 2013, 250: 139-147. [8]Alvaro J D, Tatro J B, Quillan J M,et al. Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction[J]. Mol Pharmacol, 1996, 50(3): 583-591. [9]Mansour A R, Farmer M A, Baliki M N,et al. Chronic pain: the role of learning and brain plasticity[J]. Restor Neurol Neurosci, 2014, 32(1): 129-139 [10]Shen Y, Fu W Y, Cheng E Y,et al. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism[J]. J Neurosci, 2013, 33(2): 464-472. [11]Ye Z Y, Li D P. Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats[J]. Regul Pept, 2011, 166(1/3): 112-120. [12]de-Araujo M A, Marques T E, Taniele-Silva J,et al. Identification of endogenous reference genes for the analysis of microRNA expression in the hippocampus of the pilocarpine-induced model of mesial temporal lobe epilepsy[J]. PLoS One, 2014, 9(6): e100529. [13]Andre V, Dube C, Francois J,et al. Pathogenesis and pharmacology of epilepsy in the lithium-pilocarpine model[J]. Epilepsia, 2007, 48(Suppl 5): 41-47. [14]Rakhade S N, Zhou C, Aujla P K,et al. Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures[J]. J Neurosci, 2008, 28(32): 7979-7990. [15]Rakhade S N, Fitzgerald E F, Klein P M,et al. Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures[J]. J Neurosci, 2012, 32(49): 17800-17812. [16]Dhir A. Pentylenetetrazol (PTZ) kindling model of epilepsy[J]. Curr Protoc Neurosci, 2012, Chapter 9: Unit9.37. ？
