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催化学报  2014 

Cerium(IV)sulfate:Ahighlyefficientreusableheterogeneouscatalystfortheone-potsynthesisof2,3-dihydroquinazolin-4(1H)-onesundersolvent-freeconditions

DOI: 10.1016/S1872-2067(14)60041-3, PP. 1054-1058

Keywords: Cerium(IV)sulfate,2,3-Dihydroquinazolin-4(1H)-ones,Heterogeneouscatalysis,Solvent-freeconditions

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Abstract:

?Cerium(IV)sulfatetetrahydrate,Ce(SO4)2·4H2O,isanovelinorganicsolidacidiccatalystthatefficientlycatalyzesthesynthesisof2,3-dihydroquinazolin-4(1H)-onesviatheone-potthree-componentreactionofisatoicanhydride,aromaticaldehydes,andanitrogensource(ammoniumacetate,ammoniumcarbonate,ammoniumchloride,ormethylamine)undersolvent-freeconditions.Thedesiredproductsareobtainedinshortreactiontimewithhighyields.Thecatalystisinexpensiveandreadilyavailableandcanberecoveredconvenientlyandreusedsuchthatconsiderablecatalyticactivitycanstillbeachievedafterthefifthrun.Easywork-upandavoidingtheuseofharmfulorganicsolventsareotheradvantagesofthissimpleprocedure.

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