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催化学报 2010
ChemoselectiveandCatalyticTrimethylsilylationofAlcoholsandPhenolsby1,1,1,3,3,3-HexamethyldisilazaneandCatalyticAmountsofPhMe3N+Br3–DOI: 10.1016/S1872-2067(10)60107-6, PP. 1103-1106 Keywords: phenyltrimethylammoniumtribromide,alcohol,phenol,protection,trimethylsilylation,hexamethyldisilazane Abstract: ？Anefficientprocedureforthetrimethylsilylationofalcoholsandphenolsispresented.Thecombinationof1,1,1,3,3,3-hexamethyldisilazaneandacatalyticamountofphenyltrimethylammoniumtribromide(PhMe3N+Br3?)wasfoundtobeeffectiveforthetrimethylsilylationofalcoholsandphenols.Theprotectionreactionisverysimpleandhomogenouslyperformedindichloromethaneatroomtemperatureandmildconditions.
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