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Erythribyssin H类似物的设计与合成
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Abstract:
目的：提供合成Erythribyssin H类似物(2)的路线。方法：以间苯二酚和丁香醛为起始原料，经Vilsmier- schmidet反应和酚羟基保护反应合成2-羟基4-苄氧基苯甲醛(4)和3,5-二甲氧基4-苄氧基苯甲醛(5)。然后使用McMurry交叉偶联反应得到邻乙烯基苯酚产物(6)，6在I2/K2CO3试剂作用下环合并脱保护成为Erythribyssin H类似物(2)。结果：目标化合物和相应的中间体的化学结构都经过1H-NMR
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