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Hans Journal of Medicinal Chemistry

ISSN Print: 2331-8287

ISSN Online: 2331-8295

Website: http://www.hanspub.org/journal/HJMCe

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甲氧氯普胺的量化计算理论研究
Theoretical Study on Quantitative Calculation of Metoclopramide

刘存海, 刘芬芬, 金靓婕, 郭冰

聚氨酯三维肺癌模型的建立及姜黄素药敏试验
Establishment of Three-Dimensional Polyurethane Model of Lung Cancer and Curcumin Susceptibility Test

王晗, 黄逸伦, 朱莲, 张文元, 唐靓

新型DPP-IV抑制剂的虚拟筛选与动力学验证
Virtual Screening and Kinetic Validation of Novel DPP-IV Inhibitors

刘宜周, 李烨, 孙科, 胡胜杰

SGLT-2抑制剂关键中间体及其衍生物的合成研究
Synthesis of Key Intermediates and Derivatives of SGLT-2 Inhibitors

赵彭龙, 张煜皓, 董渝文, 李桐, 张仔怡

IMiDs作为PPI稳定剂在蛋白质降解方面的研究进展
Research Progress of IMiDs as PPI Stabilizer in Protein Degradation

宋冰茹, 袁大中

基于三叶青抗动脉粥样硬化的网络药理学和分子对接研究
Network Pharmacology and Molecular Docking Study on Anti-Atherosclerosis of Tetrastigma hemsleyanum

张钰蓉, 孙智文, 王爱平

硫糖铝防治小鼠放射性口腔黏膜炎的实验研究
Experimental Study on the Prevention of Radiation-Induced Oral Mucositis in Mice by Sucralfate

徐剑浩, 罗锐, 张思, 邱景艺, 陈铭晟

羟基红花黄色素A保护心脏机制和药物吸收代谢
Mechanism of Cardiac Protection and Drug Absorption and Metabolism of Hydroxysafflor Yellow A

张丽琼

AKR1C3与疾病的关系
The Relationship between AKR1C3 and Diseases

袁大中, 宋冰茹

CA4偶氮化衍生物的合成及其性能研究
Synthesis of Azo Derivatives of CA4 and Evaluation of Their Properties

全梦香, 金佳澄, 邓双, 李思仪, 黄蓓, 张珊, 王尊元

JAK3激酶小分子抑制剂虚拟筛选设计技术的相关研究进展
Research Progress on Virtual Screening Design Techniques for Small Molecule Inhibitors of JAK3 Kinase

迟宪昊, 邓兴龙

连翘温敏口腔凝胶的制备工艺优化及性能表征
The Preparation Process Optimization and Characterization of Forsythia Thermosensitive Oral Gels

常美艳, 程敏, 李世玺, 梁旭华

铁皮石斛花多糖的提取工艺研究
Research on the Extraction Process of Polysaccharides from Dendrobium officinale Flowers

何宇城, 马国荣, 袁建锋

深共熔溶剂通过多种途径抑制肝癌细胞的增殖
Deep Eutectic Solvent Can Inhibit the Proliferation of Hepatocellular Carcinoma Cells in Many Ways

俞家伟, 方哲铖, 余立权, 喻宗繁

微量紫外–可见分光光度法测定阳离子脂质体中MicroRNA的含量
Determination of MicroRNA in Cationic Liposomes by Micro UV Spectrophotometry

贺井刚, 吴孟岚, 文鑫鑫, 谭霖, 杨从武

点击化学/生物正交反应在药物开发中的应用进展
Advances in the Application of Click Chemistry/Bioorthogonal Reactions in Drug Development

罗雅静, 孙建博

抗抑郁药物的现状与新靶点的探索
The Current Status of Antidepressant Drugs and the Exploration of New Targets

张陈平, 张翔

PARP1/CDK2双靶点抑制剂的合成及生物活性评价
Design, Synthesis and Biological Evaluation of PARP1/CDK2 Dual-Target Inhibitors

崔阳, 魏佳妮, 谌伦华

复方五指柑胶囊UPLC指纹图谱研究
UPLC Fingerprints Study of Compound Wuzhigan Capsules

汪冰冰, 陈敏怡, 冯丽洁

阿昔洛韦杂质IM5和IM6的合成研究
Synthesis of Acyclovir Impurities IM5 and IM6

张钰滢, 赵洋洋, 高小萱, 杜寒莹, 黄佳雯, 周心宇, 胡婧彤, 周德军, 赵桂琴

基于近红外光谱结合化学计量学的复方感冒灵颗粒浸膏中蒙花苷的检测研究
Detection of moisture in Radix Isatidis of Compound Ganmaoling Granules Based on Near Infrared Spectroscopy and Stoichiometry

龚小兵, 陆美清, 龙霞, 谢爱梅, 刘春方, 向阳, 陶媛, 武俊勇, 章泽恒

分散固相萃取–液相色谱串联质谱法检测动物源性食品中地西泮残留量
Determination of Diazepam Residues in An-imal Derived Foods by Liquid Chromatography Tandem Mass Spectrometry

朱小委

优思明联合二甲双胍治疗多囊卵巢综合征的疗效Meta分析
Meta-Analysis of the Efficacy of Yasmin Combined with Metformin in the Treatment of Polycystic Ovary Syndrome

何芝挺, 杨莉梅, 刘学庆

虾青素的生物活性研究进展
Research Progress on Biological Activities of Astaxanthin

蒋维维, 孙琼, 全海燕, 单志芳

基于近红外光谱结合化学计量学对淫羊藿药材中总黄酮的检测研究
Detection of Total Flavonoids in Epimedium Herbal Medicine Based on Near-Infrared Spectroscopy Combined with Chemometrics

欧阳燕琴, 李霞, 张勇, 张发森, 莫传灼, 曾艳兰, 黄元红

天然活性成分抗乳腺癌的研究进展
Research Progress of Natural Active Ingredients against Breast Cancer

冉小娟, 余相地

PD-1/PD-L1小分子抑制剂临床进展
Clinical Progress of PD-1/PD-L1 Small Molecule Inhibitors

杨帆, 刘敦恺, 王悦, 文博杰, 赖宜生

菊花黄酮类化合物抗氧化活性研究的现状、问题及展望
The Current Status, Challenges, and Prospects of Research on the Antioxidant Activity of Flavonoids in Chrysanthemums

潘戴晨, 王紫薇, 徐颂文, 蒋细旺

槟榔–草果–厚朴治疗上呼吸道感染作用机制的网络药理学研究
Study on the Mechanism of Betel Nut-Tsaoko-Magnolia Officinalis in the Treatment of Upper Respiratory Tract Infection by Network Pharmacology

王猛, 王宽宇

4-氨基磺酰基苯磺酰氯的合成
Synthesis of 4-Aminosulfonylbenzenesulfonyl Chloride

张娅, 罗成, 周志旭, 岳朝晨, 鹿田, 柴慧芳

菲啶酮和吖啶酮类天然产物合成及生物活性研究进展
Synthesis and Biological Activity Research Progress of Phenanthridinone and Quinolinone Natural Products

马钰栋, 张文渊

野菊花化学组分杀菌、消炎、抗氧化的研究现状、问题及对策
Current Research Status, Problems, and Strategies on the Antibacterial, Anti-Inflammatory, and Antioxidant Properties of Chemical Components in Wild Chrysanthemum

王紫薇, 潘戴晨, 徐颂文, 蒋细旺

1, 2, 4-三氮唑类衍生物的设计、合成及SHP-2活性评价
Design and Synthesis of 1, 2, 4-Triazole Derivatives and Evaluation of SHP-2 Activity

高立信, 王文龙

靶向冠状病毒核衣壳蛋白NTD-RNA位点的小分子抑制剂虚拟筛选
Virtual Screening of Anti-Coronavirus Small Molecule Inhibitors Targeting NTD-RNA of Nucleocapsid Protein

玄亚男, 张娜

埃博霉素类抗肿瘤药物在乳腺癌中的研究进展
Research Progress of Ebomycin Antitumor Drugs in Breast Cancer

孟雪, 胡亚妮, 周海嫔, 刘娟娟

Galt基因编辑小鼠的肠道菌群分析
Analysis of Gut Microbiota in Galt Editing Mice

季子涵, 刘桂福, 岳鹏鹏, 于鸿浩

ACSL4在肿瘤中的研究进展
Research Progress of ACSL4 in Cancer

丁喜乐, 周宸宇, 朱茜, 陈琼霞, 镇鸿燕

EGFR变构抑制剂在小细胞肺癌治疗中的作用和未来发展
The Role and Future Development of EGFR Allosteric Inhibitors in the Treatment of Small Cell Lung Cancer

贾硕磊, 周庆发

吡嗪类SHP2抑制剂的设计、合成及生物活性评价
Design, Synthesis and Biological Activity Evaluation of Pyrazine SHP2 Inhibitors

陈卓, 堵桐弘, 吕遐师, 李沛峰, 赖宜生

单硝酸异山梨酯择时释放渗透泵片在家兔体内的药动学研究
Pharmacokinetics Study of Timed- and Controlled-Release Osmotic Pump System of Isosorbide Mononitrate in Rabbits

邹青, 李平, 吕圆, 李翔, 全海燕, 彭栋梁, 梁忠厚, 赵绿英

麻黄的药理作用及其药对研究进展
Pharmacological Effects of Ephedra and Its Drug Pair Progress

叶妮, 龚年金

AGGF1-EPCs对小鼠急性肾损伤保护作用的研究
The Protective Effect Analysis of AGGF1 Primed EPCs on Acute Kidney Injury in Mice

李夏, 牧苏婉, 杨惠元, 韦妙灵, 韦柳青, 李勇

天然多糖的来源、化学结构及免疫增强活性研究
Resource, Chemical Structure and Immunomodulatory Activity of Natural Polysaccharides

张虎, 李飞, 刘鄂湖

活性炭吸附对参芪扶正稀释液四种指标成分含量的影响
The Effect of Activated Carbon Adsorption on Content of Four Indicative Constituents in Shenqi Fuzheng Diluent

刘学华, 欧志煌, 周卫, 汤志龙, 龚行楚

基于HPLC特征图谱的蜡梅花与其易混淆品梅花的鉴别研究
Identification of Flos Chimonanthi and Its Confused Product Mume Flos Based on HPLC Characteristic Chromatograms

廖明丽, 李争, 李思远, 张诗华, 刘良娟, 李雯媛, 高晗, 李军山

槲皮素的抗癌作用及机制研究进展
Research Progress on the Anti-Cancer Effects and Mechanisms of Quercetin

蒋维维, 李平, 孙琼, 全海燕

中药材太赫兹数据预处理方法的研究
Research on Preprocessing Methods of Terahertz Data for Traditional Chinese Medicine

胡相棚, 陈华林, 刘予煊, 唐德东

基于壳聚糖的胡桃醌纳米载药体系的构建及性能评价
Construction and Performance Evaluation of Juglone Nano Drug Delivery System Based on Chitosan

周伟, 常珍珍, 梁旭华

多孔淀粉益生菌微胶囊的制备及其对益生菌存活率的影响
Porous Starch Probiotic Preparation of Microcapsules and Their Effects on Probiotic Survival Rate

王熙函, 陈东晓, 陈曦, 吴佳悦, 卫馨悦, 刘明辉, 赵化冰

基于近红外光谱结合化学计量学的银杏酮酯喷干粉中的总黄酮醇苷的检测研究
Research on the Determination of Total Flavonol Glycosides in Ginkgo Ester Spray Powder Based on Near Infrared Spectroscopy and Chemometrics

黄建强, 朱宝中, 王金峰

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