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热性感染相关性癫痫综合征1例报道
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Abstract:
目的：探讨热性感染相关性癫痫综合征(febrile infection-related epilepsy syndrome, FIRES)的临床特点和诊疗对策。方法：对我院收治的1例FIRES患儿的临床资料进行回顾性分析。结果：患儿以精神行为异常起病，起病前有发热感染病史，病程中出现难治性部分性癫痫持续状态(refractory partial status epilepticus, RPSE)，经经验性抗中枢神经系统感染治疗及多种抗癫痫药物(antiepileptie drugs, AEDs)联合治疗2月，发作未控制，家属放弃治疗出院，出院后20天患儿死于癫痫持续状态(SE)。结论：FIRES临床中少见，目前治疗困难，应注意早期识别，尽早予以大剂量抗癫痫药物
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