Objective: We study the clinical characteristics of the common rat poison poisoning in children, in order to improve the understanding of this disease. Methods: We retrospectively analysed the clinical manifestations, treatment methods and treatment effect of the 98 cases of rat poison poisoning children in our hospital. Results: 92 cases were rescued successfully, and six died. Conclusion: The most important measure to rescue rat poison poisoning patients is focusing on prevention. Early diagnosis, early treatment and preventing complications can reduce fatality rate.