Objectives: To analyse the risk factors for
death as a result of pulmonary complications in kidney transplant patients.
Material and Methods: 267 patients after renal transplantation were prospectively
studied. The kidney recipients were followed for the development of pulmonary
complications and their outcome for a period of 7 years.
Different noninvasive and invasive diagnostic tests were used in cases
suspected for lung disease. Results: Risk factors for death as a result of
pulmonary complications are development of lung
diseases in the first six months after operation (P < 0.05), and immunosuppressive
regimens that include mycophenolate mofetil (HR: 3.216; 95%CI: 1.067 - 5.577; P=
0.011). The factors associated with lower rate of fatal outcome are positive serology
test for Cytomegalovirus of the recipient before transplantation (P = 0.034)
and use of azathioprine (HR: 0.720; 95%CI: 0.526 - 0.986; P=
0.04). Conclusions: The risk factors may be used to identify patients at
increased risk for death due to the pulmonary complications. Strictly monitoring
of higher-risk patients can reduce the morbidity and mortality after renal
transplantation.
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